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Image Search Results
Journal: G3: Genes|Genomes|Genetics
Article Title: Identification and Characterization of FGF2-Dependent mRNA: microRNA Networks During Lens Fiber Cell Differentiation
doi: 10.1534/g3.113.008698
Figure Lengend Snippet: Global analysis of RNAs, miRNAs, and miRNA:mRNA pairs
Article Snippet: The inverse miRNA:mRNA target correlation patterns were determined using the
Techniques:
Journal: G3: Genes|Genomes|Genetics
Article Title: Identification and Characterization of FGF2-Dependent mRNA: microRNA Networks During Lens Fiber Cell Differentiation
doi: 10.1534/g3.113.008698
Figure Lengend Snippet: Four sets of global GRNs. (A) “Early” up-miRNA:down-regulated mRNA. (B) “Late” up-miRNA:down-regulated mRNA. (C) “Early” down-miRNA:up-regulated mRNA. (D) “Late” down-miRNA:up-regulated mRNA. The diagrams were created using Cytoscape program as described in the Materials and Methods using only high-scoring and experimentally observed predictions. miRNA, triangles; mRNAs, circles; up-regulated (red); down-regulated (blue).
Article Snippet: The inverse miRNA:mRNA target correlation patterns were determined using the
Techniques:
Journal: G3: Genes|Genomes|Genetics
Article Title: Identification and Characterization of FGF2-Dependent mRNA: microRNA Networks During Lens Fiber Cell Differentiation
doi: 10.1534/g3.113.008698
Figure Lengend Snippet: A “late” connectivity network. Ten miRNAs, miR-20b, miR-145, miR-152, miR-155, miR-181a, miR-203, miR-222, miR-301a, miR-324-5p, and miR-351. (A) DNA-binding transcription factors (c-Maf, Ets1, Nfat5/OREBP, and Stc1). (B) mRNA and protein processing (Cnot6, Dicer1, Fbxo33, and Wdr47). miRNA, triangles; mRNAs, circles; up-regulated (red); down-regulated (blue).
Article Snippet: The inverse miRNA:mRNA target correlation patterns were determined using the
Techniques: Binding Assay
Journal: G3: Genes|Genomes|Genetics
Article Title: Identification and Characterization of FGF2-Dependent mRNA: microRNA Networks During Lens Fiber Cell Differentiation
doi: 10.1534/g3.113.008698
Figure Lengend Snippet: FGF2-regulated miRNAs and posttranscriptional control of c-Maf. (A) Localization of miRNA-binding regions in the mouse c-Maf 3′-UTR (NCBI Reference Sequence NM_001025577.2) and their separation into three shorter regions, WT1 (~0.8 kb), WT2 (~0.2 kb), and WT3 (~0.5 kb). These regions are evolutionary conserved among mammals. (B) Sequence alignment of individual miRNAs:3′-UTR mRNA pairs. Watson-Crick (vertical lines) and wobble (G:U) base pairing are shown. The nucleotides changed in mutated reporter plasmids are highlighted in gray. (C) Luciferase reporter assays using the WT1, WT2, and WT3. (D) Luciferase reporter assays using specific mutants of WT1, WT2, and WT3 (see panel B).
Article Snippet: The inverse miRNA:mRNA target correlation patterns were determined using the
Techniques: Control, Binding Assay, Sequencing, Luciferase
Journal: Chemical research in toxicology
Article Title: Isoprene-Derived Secondary Organic Aerosol Induces the Expression of MicroRNAs Associated with Inflammatory/Oxidative Stress Response in Lung Cells
doi: 10.1021/acs.chemrestox.9b00322
Figure Lengend Snippet: Thirty-One miRNAs Identified with Significant Differential Expression Associated with Exposure to Either IEPOX-Derived SOA or MAE-Derived SOA a
Article Snippet:
Techniques: Quantitative Proteomics
Journal: Chemical research in toxicology
Article Title: Isoprene-Derived Secondary Organic Aerosol Induces the Expression of MicroRNAs Associated with Inflammatory/Oxidative Stress Response in Lung Cells
doi: 10.1021/acs.chemrestox.9b00322
Figure Lengend Snippet: Log fold changes of miRNA expression when exposed to IEPOX- or MAE-derived SOA compared to acidified sulfate aerosol control.
Article Snippet:
Techniques: Expressing, Derivative Assay, Aerosol, Control